Fresh analysis reveals that people who stop using new slimming jabs like Wegovy and Mounjaro tend to recover shed pounds much more quickly than those who halt conventional lifestyle regimens.
Research printed in a major health publication shows that while obese individuals often shed substantial amounts of their body weight while on the medication, the weight comes back at an average rate of nearly a kilo each month upon discontinuation.
"Individuals buying these medications need to be informed of the danger of fast weight regain when the therapy concludes," warns expert Dr. Susan Jebb.
That rate of regain suggests a return to pre-treatment weight in about a year and a half.
Comparing Approaches
The analysis, which looked at dozens of trials involving over 9,000 of patients, contrasted the effects of GLP-1 agonists with older methods.
The team note that people who shed pounds through dieting typically see a less rapid weight regain—perhaps 100 grams monthly—post-intervention.
Explaining the Quick Rebound
Experts suggest the mechanism of the injections explains the amplified regain.
GLP-1 drugs copy a natural hormone called GLP-1, which helps regulate feelings of fullness.
"Artificially providing the hormone concentrations far above than the body's typical production might result in the system to generate a reduced amount of its own natural GLP-1, and may also lessen sensitivity to its actions," explained Dr. Adam Collins, a nutrition researcher.
"Stopping of this hormone supplement results in hunger is unsuppressed, making excessive eating a significant risk."
An Ongoing Issue?
The NHS recommend the injections for individuals with obesity-related health risks, accompanied by recommended diet and exercise modifications.
Professionals contend that, given the likelihood of relapse, the treatment might need to be ongoing.
This perspective is echoed by drug manufacturers, who state that the results "underscore the persistent character of excess weight," akin to managing diseases like high blood pressure.
User Testimonies
Users who have discontinued the medication report a powerful resurgence of hunger.
"It was like a switch flipping and I was suddenly ravenous," described one woman.
The struggle is compounded if patients have not adopted sustainable lifestyle or habit modifications during therapy.
Growing Use
Recent estimates show that millions of adults in the UK have used weight-loss jabs in the past year, with interest remaining high.
- Use is more common among women compared to males.
- The middle-aged demographic shows the greatest usage rates.
- Many obtain the drugs through private prescriptions rather than public health services.
In conclusion, clinicians stress that while the jabs are potent tools for shedding pounds, they are not a magic fix and maintained weight loss likely depends on ongoing behavioural support.
